| Characteristic | Description |
|---|---|
| Generic Name | Tadalafil |
| Brand Names | Cialis, Erectafil |
| Strengths | 2.5 mg, 5 mg, 10 mg, 20 mg |
| Form | Tablet |
| Therapeutic Class | PDE5 Inhibitor |
| Usage | Treatment of Erectile Dysfunction |
| Discover More | |
Pharmacokinetics
The pharmacokinetics of Erectafil revolve around its absorption, distribution, metabolism, and excretion. This PDE5 inhibitor reaches peak plasma concentration within two hours post-administration. The absolute bioavailability of tadalafil remains unquantified. The systemic distribution demonstrates a steady state volume of approximately 63 liters, signifying its widespread distribution within tissues. It is metabolized predominantly by the CYP3A4 hepatic enzyme, resulting in the principal metabolite, catechol. Excretion is through feces (61%) and urine (36%), with a half-life of 17.5 hours allowing for sustained action.
Areas of Use
Erectafil 20mg serves primarily in erectile dysfunction therapy, enhancing penile blood flow. It achieves efficacy by inhibiting PDE5, facilitating smooth muscle relaxation in corpus cavernosum. Beyond this, it finds application in benign prostatic hyperplasia, alleviating urinary symptoms. Off-label, it may aid in pulmonary arterial hypertension, demonstrating vascular effects. The therapeutic flexibility of Erectafil underscores its pivotal role in urological and cardiovascular conditions.
Erectafil Precautions
Caution is advised when prescribing Erectafil to individuals with cardiovascular conditions. Patients with myocardial infarction history should approach with care. Liver and kidney impairments necessitate dosage adjustments due to altered drug clearance. Concomitant use with nitrates contraindicates due to potential hypotension. Advisement against grapefruit juice is prudent as it alters tadalafil metabolism. These precautions aim to minimize risk and optimize therapeutic benefit.
Erectafil Interactions
Drug interactions with Erectafil 5mg are noteworthy. Potent inhibitors of CYP3A4 like ketoconazole increase tadalafil plasma concentration, necessitating caution. Conversely, inducers such as rifampicin reduce efficacy. Co-administration with antihypertensives requires vigilance due to additive blood pressure reduction. Alpha-blockers combined with tadalafil may exacerbate hypotension. Patients should disclose all medications to avert adverse interactions.
| Drug Interaction | Effect |
|---|---|
| Ketoconazole | Increased Tadalafil Levels |
| Rifampicin | Decreased Efficacy |
How to Cope with Side Effects of Erectafil
Erectafil side effects encompass headache, dyspepsia, and back pain. Hydration and rest mitigate headaches. Taking Erectafil with food can reduce dyspeptic symptoms. Persistent or severe adverse effects warrant medical consultation. Allergic reactions, though rare, necessitate immediate discontinuation and medical attention. Informing healthcare providers of side effects facilitates prompt management.
Erectafil for Sale Online
The availability of Erectafil online facilitates accessibility. Ensure procurement from reputable pharmacies. Verification of legitimacy prevents counterfeit risks. Online platforms offer discretion and convenience, with competitive pricing. Consultation with healthcare professionals remains vital, ensuring appropriate use and monitoring. Patients benefit from careful sourcing and guidance when purchasing medications online.
- Consult your doctor before starting any new medication.
- Read all provided information before taking Erectafil.
- Be aware of potential side effects and interactions.
In essence, Erectafil represents a critical option in erectile dysfunction management, with a well-defined pharmacokinetic profile and multifaceted use cases. Proper precautions, interaction awareness, and side effect management are integral to its safe application.
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